Webcitalopram clomipramine diazepam imipramine: lansoprazole phenytoin omeprazole R-warfarin: CYP2D6: amiodarone chloroquine cimetidine clomipramine diphenhydramine fluoxetine fluphenazine haloperidol paroxetine perphenazine propafenone propoxyphene quinacrine quinidine ritonavir sertaline terbinafine thioridazine: None: amitriptyline … WebEscitalopram is metabolised by the cytochrome P450 (CYP) isoenzymes CYP2C19, CYP2D6 and CYP3A4. However, ritonavir, a potent inhibitor of CYP3A4, does not affect …
Citalopram Monograph for Professionals - Drugs.com
WebFluoxetine and paroxetine are potent CYP2D6 inhibitors, whereas fluoxetine's main metabolite, norfluoxetine, has a moderate inhibitory effect on CYP3A4. Sertraline is a … WebJul 13, 2024 · Antidepressants used in therapeutic dosing ranges are associated with causing several adverse drug reactions including hepatotoxicity. Paroxetine, fluoxetine, fluvoxamine, citalopram, mirtazapine and venlafaxine are associated with reversible liver injury upon discontinuation of the agent. baldi philasd
Selective serotonin reuptake inhibitors and cytochrome P …
WebApr 18, 2024 · Citalopram is metabolized to 2 metabolites, each having antidepressant activity considered to be 13% that of citalopram. Maternal Levels. In a pooled analysis of serum levels from published studies and … WebSep 15, 2024 · Citalopram (Monograph) Brand name: CeleXA Drug class: Selective Serotonin-reuptake Inhibitors - Serotonin-reuptake Inhibitors - SSRIs VA class: CN609 Chemical name: 1- [3- (Dimethylamino)-propyl]-1- (p-fluorophenyl)-5-phthalancarbonitrile Molecular formula: C 20 H 21 FN 2 O CAS number: 59729-33-8 Medically reviewed by … WebDec 24, 2015 · Citalopram is metabolized mainly in the liver via N-demethylation to its main metabolite, demethylcitalopram by CYP2C19 and CYP3A4 7. Other metabolites include … baldi plush target