Web13 apr 2024 · Experimental infection of mice with L. donovani was conducted as previously described . Briefly, L. donovani promastigotes in the late log or stationary phase were washed and resuspended with PBS at a concentration of 1 × 10 8 cells/mL. Mice were infected with 1 × 10 7 L. donovani promastigotes by intravenous injection into the tail vein. Web8 nov 2024 · Leishmania donovani is responsible for visceral leishmaniasis, a neglected and lethal parasitic disease with limited treatment options and no vaccine. The study of L. donovani has been hindered by ...
Pathogens Free Full-Text Leishmania Infection-Induced …
Web1 nov 2024 · Leishmania donovani complex genetic distances were assessed relative to other Leishmania complexes, i.e. those of L. major and L. tropica, by both NN analysis and systematic pairwise comparison of whole-genome sequences.Whatever the dataset used (i.e. an MLSA scheme based on seven genes, partial hsp70 gene or complete got gene … Web29 dic 2024 · Visceral leishmaniasis is caused by the Leishmania donovani species complex that can spread to internal organs and leading to death if not treated on time. Diagnosis of leishmaniasis is based on clinical signs and symptoms, microscopy, serological and molecular techniques. Because of a broad spectrum of diverse clinical … bryce star trek discovery
In-silico design of an immunoinformatics based multi-epitope …
Web13 apr 2024 · Experimental infection of mice with L. donovani was conducted as previously described . Briefly, L. donovani promastigotes in the late log or stationary phase were … Web10 dic 2024 · Gabriel H Negreira, Pieter Monsieurs, Hideo Imamura, Ilse Maes, Nada Kuk, Akila Yagoubat, Frederik Van den Broeck, Yvon Sterkers, Jean-Claude Dujardin, Malgorzata A Domagalska, High throughput single-cell genome sequencing gives insights into the generation and evolution of mosaic aneuploidy in Leishmania donovani, Nucleic Acids … Web5 ago 2024 · Evaluation of epitope conservancy and population coverage analysis. The selected epitopes of all the proteins except ALSP were fairly conserved among four selected strains of L. donovani.A moderate level of epitope conservancy was noted in the JPCM5 strain of L. infantum and poor conservancy was noted among L. braziliensis and L. … bryce stephens allstate