Web11 Jan 2024 · The list contains a variety of drugs from heart medications to antibiotics, although not all the drugs on the list may be affected by CBD-only products (some are only affected by THC). Potentially serious drug interactions with CBD included. a common blood thinner, warfarin; a heart rhythm medication, amiodarone; a thyroid medication, … WebWarfarin THC and CBD increase warfarin levels (Yamaori et al 2012). Frequent cannabis use has been associated with increased INR . Alcohol Alcohol may ni crease THC levels (Hartman 2015). Theophylline Smoked cannabsi can decrease theophylline levels (Stout and Cimino 2014). Indinavir or nelfinavir
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WebHigh doses of ketoconazole or itraconazole (>200 mg/day) are not recommended. Life-threatening and fatal drug interactions have been reported in patients treated with colchicine and ritonavir. For patients with renal and/or hepatic impairment. co-administration of colchicine with PAXLOVID is contraindicated (see. WebCannabis products are compounds derived from the cannabis plant. These products are being used with increasing frequency in the treatment of epilepsy and other chronic diseases. While generally felt to be safe due to their natural origin, data reveals interactions with other pharmaceuticals. happy wraps bellefonte pa
Cannabis Use Leads to INR Elevation in Warfarin-Treated Patient
Web8 Oct 2024 · Here’s a breakdown of medications known to have drug-drug interactions with THC and/or CBD. Warfarin. Use of cannabinoids increases the risk of bleeding in patients taking warfarin. Warfarin has a narrow therapeutic window, so even minor changes to the anticoagulant’s effect can increase the risk of bleeding and thrombosis. Because THC and … WebThe cannabinoid THC could inhibit cytochrome P450 enzyme CYP2C9. This enzyme is responsible for metabolizing Warfarin. CBD has been shown to inhibit CYP2C19, which converts clopidogrel to its active thiol metabolite. So in short, it does appear CBD could interfere with the metabolism of blood thinners on some level. WebObjective: We have reported a case of a drug-drug interaction (DDI) involving warfarin and Δ-9-tetrahydrocannabinol (THC) that resulted in a supratherapeutic international normalized ratio (INR) level. The purpose of this case report is to highlight the possibility of a pharmacokinetic DDI between THC and warfarin. Case summary: A 67-year-old Caucasian … happy wq